Current Issue February 2012, Vol. 75, No. 2

The Italian Association of Thoracic Oncology (AIOT) was founded in July 2007 in order to improve knowledge and research in the field of thoracic oncology in Italy, through the collaboration of oncologists, radiotherapists, surgeons and researchers. The aim of the association is to create a platform for cultural and scientific discussion among the different professional trainers who play an important part in the diagnostic and therapeutic runs. A further aim is to support and increase clinical research and medical training.

The AIOT is also actively involved with the Italian School of Thoracic Oncology (SIOT) located in Frascati, Rome in the wonderful area of Castelli Romani, as well as in the organization of highly qualified educational events. Moreover with 380 members, the AIOT is currently setting up an international board of key opinion leaders.

• Verification of beam delivery using fibrosis after proton beam irradiation to the lung tumor
  27 January 2012

  Nobuyoshi Fukumitsu, Yoshiko Oshiro, Takayuki Hashimoto, Toshiyuki Okumura, Masashi Mizumoto, Takashi Moritake, Koji Tsuboi, Takeji Sakae, Hideyuki Sakurai

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  Abstract: Background and purpose: To investigate the geometrical accuracy in proton beam therapy (PBT) to the lung by comparing the location of the fibrosis after PBT and the tumor using less invasive...

• EGFR–TKI resistant non-small cell lung cancer (NSCLC): New developments and implications for future treatment
  27 January 2012

  Wolfram Brugger, Michael Thomas

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  Abstract: Treatment with receptor-tyrosine kinase inhibitors (TKIs) has improved progression-free and overall survival in patients with advanced non-small cell lung cancer (NSCLC). One major target fo...

• Benefits and risks of using erythropoiesis-stimulating agents (ESAs) in lung cancer patients: Study-level and patient-level meta-analyses
  25 January 2012

  Johan Vansteenkiste, John Glaspy, David Henry, Heinz Ludwig, Robert Pirker, Dianne Tomita, Helen Collins, Jeffrey Crawford

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  Abstract: In anemic patients receiving myelosuppressive chemotherapy, erythropoiesis-stimulating agents (ESAs) raise hemoglobin levels and reduce transfusion requirements, but ESA-related safety conce...

• Maintenance treatment of advanced non-small-cell lung cancer: Results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology
  24 January 2012

  Cesare Gridelli, Filippo de Marinis, Massimo Di Maio, Andrea Ardizzoni, Chandra P. Belani, Federico Cappuzzo, Fortunato Ciardiello, Panagiotis Fidias, Luis Paz-Ares, Francesco Perrone, Robert Pirker, Luigi De Petris, Rolf Stahel

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  Abstract: Several randomized trials have recently investigated the role of maintenance treatment for patients with advanced non-small-cell lung cancer (NSCLC) with responding or stable disease after c...

• Differential effect of age on survival in advanced NSCLC in women versus men: Analysis of recent Eastern Cooperative Oncology Group (ECOG) studies, with and without bevacizumab
  24 January 2012

  H.A. Wakelee, S.E. Dahlberg, J.R. Brahmer, J.H. Schiller, M.C. Perry, C.J. Langer, A.B. Sandler, C.P. Belani, D.H. Johnson, Eastern Cooperative Oncology Group

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  Abstract: Background: The impact of age on prognosis in advanced stage non-small cell lung cancer (NSCLC) may differ by sex. Patients and methods: Eligible patients (N=1590) from E1594, a 4-arm platin...

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