FDG-PET maximum standardised uptake value is associated with variation in survival: Analysis of 498 lung cancer patients

Received 4 July 2006; received in revised form 13 September 2006; accepted 18 September 2006.

Summary

We sought to establish the extent to which tumour uptake of [18F]-fluoro2-deoxy-glucose is associated with survival in patients with primary lung cancer. From our analysis of data concerning 498 lung cancer patients, including surgical and non-surgical cases, we conclude that there is a clear association between higher tumour uptake of glucose and worse survival.

Keywords: Lung cancer, Imaging, PET, SUV, Prognosis, Survival

a The Thoracic Unit, Guy's Hospital, London SE1 9RT, United Kingdom

b Clinical Operational Research Unit, UCL, London, United Kingdom

c PET Imaging Centre, St. Thomas’ Hospital, London, United Kingdom

Corresponding author. Tel.: +44 79 57 16 87 54; fax: +44 20 77 01 87 37.

PII: S0169-5002(06)00489-2

doi:10.1016/j.lungcan.2006.09.010

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