Lung Cancer
Volume 57, Issue 3 , Pages 407-409, September 2007

Malignant pleural mesothelioma: Two cases in first degree relatives

Department of Medical Oncology, Royal Marsden Hospital, Sutton, SURREY SM2 5PT, United Kingdom

Received 18 July 2006; received in revised form 1 February 2007; accepted 8 February 2007.

Summary 

We report two cases of malignant pleural mesothelioma in first degree relatives arising within weeks of each other. The patients had a shared exposure to asbestos and age difference of over 20 years at time of presentation. In both cases, the anatomical pattern was similar and unusual for mesothelioma and initial histology was reported for both as non-small cell lung cancer. Both patients were treated with platinum-based combination chemotherapy.

Abbreviations: CT, computed tomography, RECIST, response evaluation criteria in solid tumors, NF2, neurofibromatosis 2

Keywords: Malignant mesothelioma, Non-small cell lung cancer, Platinum-based combination chemotherapy

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PII: S0169-5002(07)00118-3

doi:10.1016/j.lungcan.2007.02.005

Lung Cancer
Volume 57, Issue 3 , Pages 407-409, September 2007

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