Lung Cancer
Volume 66, Issue 3 , Pages 298-304 , December 2009

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

  • Dong Wang

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
    • The first two authors contributed equally to this work.
    • Corresponding Author InformationCorresponding author. Tel.: +86 23 68757151; fax: +86 23 68757151.
  • ,
  • De-Bing Xiang

      Affiliations

    • Department of Pathology, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
    • The first two authors contributed equally to this work.
  • ,
  • Xue-qin Yang

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
  • ,
  • Lian-Sheng Chen

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
  • ,
  • Meng-Xia Li

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
  • ,
  • Zhao-Yang Zhong

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
  • ,
  • Yun-Song Zhang

      Affiliations

    • Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China

Received 5 October 2008 ,Revised 19 January 2009 ,Accepted 22 February 2009.

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PII: S0169-5002(09)00118-4

doi: 10.1016/j.lungcan.2009.02.019

Lung Cancer
Volume 66, Issue 3 , Pages 298-304 , December 2009