Lung Cancer
Volume 67, Issue 3 , Pages 296-300 , March 2010

Tumor size matters differently in pulmonary adenocarcinoma and squamous cell carcinoma

  • Pei-Ying Lin

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Yeun-Chung Chang

      Affiliations

    • Department of Radiology, National Taiwan University Hospital, Taipei, Taiwan
  • ,
  • Hsuan-Yu Chen

      Affiliations

    • Institute of Statistical Science, Academia Sinica, Taipei, Taiwan
  • ,
  • Chen-Hao Chen

      Affiliations

    • College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • Hung-Chang Tsui

      Affiliations

    • College of Medicine, National Taiwan University, Taipei, Taiwan
  • ,
  • Pan-Chyr Yang

      Affiliations

    • Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    • College of Medicine, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author at: College of Medicine, National Taiwan University, Department of Internal Medicine, National Taiwan University Hospital, #7, Chung-Shan South Road, Taipei 100, Taiwan. Tel.: +886 2 2356 2905; fax: +886 2 2358 2867.

Received 30 January 2009 ,Revised 11 March 2009 ,Accepted 27 April 2009.

References 

  1. Veeramachaneni NK, Battafarano RJ, Meyers BF, Zoole JB, Patterson GA. Risk factors for occult nodal metastasis in clinical T1N0 lung cancer: a negative impact on survival. Eur J Cardiothorac Surg. 2008;33:466–469
  2. Flieder DB, Port JL, Korst RJ, Christos PJ, Levin MA, Becker DE, et al. Tumor size is a determinant of stage distribution in T1 non-small cell lung cancer. Chest. 2005;128:2304–2308
  3. Christian C, Erica S, Morandi U. The prognostic impact of tumor size in resected stage I non-small cell lung cancer: evidence for a two thresholds tumor diameters classification. Lung Cancer. 2006;54:185–191
  4. Henschke CI, Yankelevitz DF, Miettinen OS. International Early Lung Cancer Action Program Investigators. Computed tomographic screening for lung cancer: the relationship of disease stage to tumor size. Arch Intern Med. 2006;166:321–325
  5. Mujoomdar A, Austin JH, Malhotra R, Powell CA, Pearson GD, Shiau MC, et al. Clinical predictors of metastatic disease to the brain from non-small cell lung carcinoma: primary tumor size, cell type, and lymph node metastases. Radiology. 2007;242:882–888
  6. Gajra A, Newman N, Gamble GP, Abraham NZ, Kohman LJ, Graziano SL. Impact of tumor size on survival in stage IA non-small cell lung cancer: a case for subdividing stage IA disease. Lung Cancer. 2003;42:51–57
  7. Padilla J, Calvo V, Peñalver JC, Sales G, Morcillo A. Surgical results and prognostic factors in early non-small cell lung cancer. Ann Thorac Surg. 1997;63:324–326
  8. Clinical tumor size prognosis in lung cancer . Bronchogenic Carcinoma Cooperative Group of the Spanish Society of Pneumology and Thoracic Surgery (GCCB-S). Eur Respir J. 1999;14:812–816
  9. Groome PA, Bolejack V, Crowley JJ, Kennedy C, Krasnik M, Sobin LH, et al. The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol. 2007;2:694–705
  10. Chen KY, Chang CH, Yu CJ, Kuo SH, Yang PC. Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma. Cancer. 2005;103:2566–2574
  11. Kabat GC. Recent developments in the epidemiology of lung cancer. Semin Surg Oncol. 1993;9:73–79
  12. Watkin SW, Hayhurst GK, Green JA. Time trends in the outcome of lung cancer management: a study of 9,090 cases diagnosed in the Mersey Region, 1974–86. Br J Cancer. 1990;61:590–596
  13. Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97:339–346
  14. Toh CK, Gao F, Lim WT, Leong SS, Fong KW, Yap SP, et al. Never-smokers with lung cancer: epidemiologic evidence of a distinct disease entity. J Clin Oncol. 2006;24:2245–2251
  15. Wisnivesky JP, Yankelevitz D, Henschke CI. Stage of lung cancer in relation to its size: part 2. Evidence. Chest. 2005;127:1136–1139
  16. Fokas E, Engenhart-Cabillic R, Daniilidis K, Rose F, An HX. Metastasis: the seed and soil theory gains identity. Cancer Metastasis Rev. 2007;26:705–715
  17. Bajard A, Westeel V, Dubiez A, Jacoulet P, Pernet D, Dalphin JC, et al. Multivariate analysis of factors predictive of brain metastases in localized non-small cell lung carcinoma. Lung Cancer. 2004;45:317–323
  18. Cox JD, Yesner RA. Adenocarcinoma of the lung: recent results from the Veterans Administration Lung Group. Am Rev Respir Dis. 1979;120:1025–1029
  19. Figlin RA, Piantadosi S, Feld R. Intracranial recurrence of carcinoma after complete surgical resection of stage I, II, and III non-small-cell lung cancer. N Engl J Med. 1988;318:1300–1305
  20. Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350:2129–2139
  21. Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, et al. EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA. 2004;101:13306–13311
  22. Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc. 2008;83:584–594
  23. Toh CK. The changing epidemiology of lung cancer. Methods Mol Biol. 2009;472:397–411
  24. Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst. 1999;21:1194–1210
  25. Subramanian J, Govindan R. Molecular genetics of lung cancer in people who have never smoked. Lancet Oncol. 2008;9:676–682

PII: S0169-5002(09)00255-4

doi: 10.1016/j.lungcan.2009.04.017

Lung Cancer
Volume 67, Issue 3 , Pages 296-300 , March 2010