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Lung Cancer
Volume 68, Issue 1
, Pages 58-65
, April 2010
LAT1 expression in non-small-cell lung carcinomas: Analyses by semiquantitative reverse transcription-PCR (237 cases) and immunohistochemistry (295 cases)
References
- . Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66
- . Targeted therapy for non-small cell lung cancer. Semin Thorac Cardiovasc Surg. 2005;17:199–204
- . Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev. 1990;70:43–77
- . Heteromeric amino acid transporters: biochemistry, genetics, and physiology. Am J Physiol Renal Physiol. 2000;281:F995–F1018
- . Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity. J Toxicol Sci. 2003;28:1–17
- . Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. Curr Drug Metab. 2001;2:339–354
- . Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J Biol Chem. 1998;273:23629–23632
- Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Nature. 1998;395:288–291
- . Expression of l-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models. J Surg Oncol. 2001;78:265–271
- . Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Res. 1989;17:1915–1931
- . TA1, a highly conserved oncofetal complementary DNA from rat hepatoma, encodes an integral membrane protein associated with liver development, carcinogenesis, and cell activation. Cancer Res. 1995;55:1152–1159
- . Functional and molecular characteristics of system L in human breast cancer cells. Biochim Biophys Acta. 2003;1611:81–90
- . Overexpression of LAT1/CD98 light chain is sufficient to increase system l-amino acid transport activity in mouse hepatocytes but not fibroblasts. J Biol Chem. 2001;276:16877–16884
- LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung. Virchows Arch. 2006;448:142–150
- . The World Health Organization: Histological Typing of Lung and Pleural Tumours. third ed.. 1999;p. 36
- . International Union against Cancer: TNM Classification of Malignant Tumours. 6th ed.. New York: Wiley-Liss Inc.; 2002;
- Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I–III nonsmall cell lung cancer. Br J Cancer. 2008;98:742–748
- Expression of a system L neutral amino acid transporter at the blood-brain barrier. Neuroreport. 2000;11:3507–3511
- . Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. J Biol Chem. 1999;274:19745–19751
PII: S0169-5002(09)00322-5
doi: 10.1016/j.lungcan.2009.05.020
© 2009 Elsevier Ireland Ltd. All rights reserved.
« Previous
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Lung Cancer
Volume 68, Issue 1
, Pages 58-65
, April 2010
