« Previous
Next »
Lung Cancer
Volume 69, Issue 1
, Pages 26-32
, July 2010
Thromboxane receptor α mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells
References
- . Angiogenesis. J Biol Chem. 1992;267:10931–10934
- . Mechanisms of angiogenesis and arteriogenesis. Nat Med. 2000;6:389–395
- . The biology of VEGF and its receptors. Nat Med. 2003;9:669–676
- Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. J Biol Chem. 1994;269:6271–6274
- . Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. J Clin Invest. 1995;95:1798–1807
- Expression and regulation of vascular endothelial growth factor in human pulmonary epithelial cells. Am J Physiol. 2000;279:L371–L378
- . Tumorigenesis and the angiogenic switch. Nat Rev Cancer. 2003;3:401–410
- Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP. Am J Respir Cell Mol Biol. 1997;17:748–756
- Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts. J Clin Invest. 1994;93:2490–2496
- Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells. J Biol Chem. 2006;281:18601–18609
- . Prostanoid receptors and phosphatidyl inositol 3-kinase: a pathway to cancer?. Trends Pharmacol Sci. 2003;24:335–340
- . Prostanoid receptor signaling relevant to tumor growth and angiogenesis. Trends Pharmacol Sci. 2003;24:524–529
- . Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane receptor. J Biol Chem. 1994;269:19256–19261
- Increased thromboxane B2 levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma. Cancer Lett. 2006;234:193–198
- . Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer. Int Semin Surg Oncol. 2005;2:23–30
- Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer. Cancer Res. 2005;65:11581–11587
- Gene transfer of thromboxane A2 synthase and prostaglandin I2 synthase antithetically altered tumor angiogenesis and tumor growth. Cancer Res. 2002;62:63–66
- . Glycogen synthase kinase-3 phosphorylation, T-cell factor signaling activation and cell morphology change following stimulation of thromboxane receptor α. J Pharmacol Exp Ther. 2006;317:267–274
- . Activation of thromboxane receptor α induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cell. Biochem Pharmacol. 2007;74:787–800
- . PhosphorylatIon and desensitization of the human thromboxane receptor by G protein-coupled receptor kinases. J Pharmacol Exp Ther. 2001;298:1243–1251
- . Quantitation of mRNA for vitamin D metabolic enzymes CYP27B1 and CYP24 and vitamin D receptor in kidney using real time reverse transcriptase-polymerase chain reaction. J Mol Endocrinol. 2003;31:123–132
- . Tai HH. NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogenesis. 2005;26:65–72
- Characterization of a 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist. J Pharmacol Exp Ther. 1989;251:557–562
- . Regulation of extracellular signal-regulated kinase cascades by α- and β-isoforms of the human thromboxane A2 receptor. Mol Pharmacol. 2002;61:817–831
- . Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000;351:95–105
- . What is the evidence that tumors are angiogenesis dependent?. J Natl Cancer Inst. 1996;82:4–6
- Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer. Arch Surg. 1997;132:541–546
- . Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell. 1998;93:705–716
- Host prostaglandin E2-EP3 signaling regulates tumor-associated angiogenesis and tumor growth. J Exp Med. 2003;197:221–231
- . Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. Cancer Res. 2003;63:2330–2334
- . Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Res. 1999;59:4574–4577
- Thromboxane A2 regulation of endothelial cell migration, angiogenesis and tumor metastasis. Biochem Biophys Res Commun. 2000;267:245–251
- Highly accumulated platelet vascular endothelial growth factor in coagulant thrombotic region. J Thromb Haemost. 2003;1:2589–2593
- The functional role of blood platelet components in angiogenesis. Thromb Haemost. 2004;92:394–402
- Adenylate cyclase/protein kinase A signaling pathway enhances angiogenesis through induction of vascular endothelial growth factor in vivo. Jpn J Pharmacol. 2001;87:181–188
- . EP2 and EP4 prostanoid receptor signaling. Life Sci. 2003;74:143–153
- Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature. 1993;315:166–170
- . Two thromboxane A2 receptors isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to leu mutation. J Clin Invest. 1996;97:949–956
- . Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cells differentiation and migration. Circ Res. 2004;95:372–379
- Prostaglandin E2 activates mitogen-activated protein kinase/ERK pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res. 2005;65:6275–6281
PII: S0169-5002(09)00493-0
doi: 10.1016/j.lungcan.2009.09.009
© 2009 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Lung Cancer
Volume 69, Issue 1
, Pages 26-32
, July 2010
