Lung Cancer
Volume 67, Issue 3 , Pages 275-281 , March 2010

Source-specific effects of micronutrients in lung cancer prevention

  • Nina Roswall

      Affiliations

    • Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark
    • Corresponding Author InformationCorresponding author. Tel.: +45 35 25 77 14.
  • ,
  • Anja Olsen

      Affiliations

    • Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark
  • ,
  • Jane Christensen

      Affiliations

    • Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark
  • ,
  • Lars O. Dragsted

      Affiliations

    • Faculty of Life Sciences, Department of Human Nutrition, University of Copenhagen, Rolighedsvej 30, DK-1958 Frederiksberg C, Denmark
  • ,
  • Kim Overvad

      Affiliations

    • Department of Clinical Epidemiology, Aarhus University Hospital, Sdr. Skovvej 15, Box 365, DK-9000 Aalborg, Denmark
  • ,
  • Anne Tjønneland

      Affiliations

    • Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark

Received 25 August 2009 ,Revised 9 November 2009 ,Accepted 13 November 2009.

References 

  1. Block G, Patterson B, Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer. 1992;18:1–29
  2. Peto R, Doll R, Buckley JD, Sporn MB. Can dietary beta-carotene materially reduce human cancer rates?. Nature. 1981;290:201–208
  3. The Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med. 1994;330:1029–1035
  4. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996;334:1145–1149
  5. Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334:1150–1155
  6. Omenn GS. Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future. Eur J Cancer Prev. 2007;16:184–191
  7. Kristal AR, Lippman SM. Nutritional prevention of cancer: new directions for an increasingly complex challenge. J Natl Cancer Inst. 2009;101:363–365
  8. Tjonneland A, Olsen A, Boll K, Stripp C, Christensen J, Engholm G, et al. Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: a population-based prospective cohort study of 57,053 men and women in Denmark. Scaninavian J Pub Health. 2007;35(4):432–441
  9. Overvad K, Tjonneland A, Haraldsdottir J, Ewertz M, Jensen OM. Development of a semiquantitative food frequency questionnaire to assess food, energy and nutrient intake in Denmark. Int J Epidemiol. 1991;20:900–905
  10. Tjonneland A, Overvad K, Haraldsdottir J, Bang S, Ewertz M, Jensen OM. Validation of a semiquantitative food frequency questionnaire developed in Denmark. Int J Epidemiol. 1991;20:906–912
  11. Tjonneland A, Haraldsdottir J, Overvad K, Stripp C, Ewertz M, Jensen OM. Influence of individually estimated portion size data on the validity of a semiquantitative food frequency questionnaire. Int J Epidemiol. 1992;21:770–777
  12. Haraldsdottir J, Tjonneland A, Overvad K. Validity of individual portion size estimates in a food frequency questionnaire. Int J Epidemiol. 1994;23:786–796
  13. Storm HH, Michelsen EV, Clemmensen IH, Pihl J. The Danish Cancer Registry—history, content, quality and use. Dan Med Bull. 1997;44:535–539
  14. World Health Organization. International Statistical Classification of Diseases and Related Health Problems 10th Revision. http://www.who.int/classifications/apps/icd/icd10online; 2009. 16-3-2009. Ref Type: Electronic Citation.
  15. Sundhedsstyrelsen. Sundhedsstyrelsens officielle Snomed-klassifikation. http://www.patobank.dk/Snomed/SKSbase.xls; 2009. 9-1-2008. Ref Type: Electronic Citation.
  16. Greenland S. Avoiding power loss associated with categorization and ordinal scores in dose–response and trend analysis. Epidemiology. 1995;6:450–454
  17. Greenland S. Dose–response and trend analysis in epidemiology: alternatives to categorical analysis. Epidemiology. 1995;6:356–365
  18. Nordisk Ministerråd. Nordic Nutrition Recommendations 2004. Integrating nutrition and physical activity. Copenhagen: Nordic Council of Ministers; 2004.
  19. Ruano-Ravina A, Figueiras A, Freire-Garabal M, Barros-Dios JM. Antioxidant vitamins and risk of lung cancer. Curr Pharm Des. 2006;12:599–613
  20. Knekt P, Jarvinen R, Seppanen R, Rissanen A, Aromaa A, Heinonen OP, et al. Dietary antioxidants and the risk of lung cancer. Am J Epidemiol. 1991;134:471–479
  21. Shibata A, Paganini-Hill A, Ross RK, Henderson BE. Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: a prospective study. Br J Cancer. 1992;66:673–679
  22. Yong LC, Brown CC, Schatzkin A, Dresser CM, Slesinski MJ, Cox CS, et al. Intake of vitamins E, C, and A and risk of lung cancer. The NHANES I epidemiologic followup study. First National Health and Nutrition Examination Survey. Am J Epidemiol. 1997;146:231–243
  23. Ocke MC, Bueno-de-Mesquita HB, Feskens EJ, van Staveren WA, Kromhout D. Repeated measurements of vegetables, fruits, beta-carotene, and vitamins C and E in relation to lung cancer. The Zutphen Study. Am J Epidemiol. 1997;145:358–365
  24. Bandera EV, Freudenheim JL, Marshall JR, Zielezny M, Priore RL, Brasure J, et al. Diet and alcohol consumption and lung cancer risk in the New York State Cohort (United States). Cancer Causes Control. 1997;8:828–840
  25. Voorrips LE, Goldbohm RA, Brants HA, van Poppel GA, Sturmans F, Hermus RJ, et al. A prospective cohort study on antioxidant and folate intake and male lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2000;9:357–365
  26. Slatore CG, Littman AJ, Au DH, Satia JA, White E. Long-term use of supplemental multivitamins, vitamin C, vitamin E, and folate does not reduce the risk of lung cancer. Am J Respir Crit Care Med. 2008;177:524–530
  27. Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA. 2005;294:56–65
  28. Lin J, Cook NR, Albert C, Zaharris E, Gaziano JM, Van DM, et al. Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. J Natl Cancer Inst. 2009;101:14–23
  29. Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2009;301:39–51
  30. Cho E, Hunter DJ, Spiegelman D, Albanes D, Beeson WL, van den Brandt PA, et al. Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: a pooled analysis of 8 prospective studies. Int J Cancer. 2006;118:970–978
  31. Zhang SM, Cook NR, Albert CM, Gaziano JM, Buring JE, Manson JE. Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial. JAMA. 2008;300:2012–2021
  32. Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, et al. Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA. 2007;297:2351–2359
  33. Figueiredo JC, Grau MV, Haile RW, Sandler RS, Summers RW, Bresalier RS, et al. Folic acid and risk of prostate cancer: results from a randomized clinical trial. J Natl Cancer Inst. 2009;101:432–435
  34. Kim YI. Folate: a magic bullet or a double edged sword for colorectal cancer prevention?. Gut. 2006;55:1387–1389
  35. Greenwald P. Beta-carotene and lung cancer: a lesson for future chemoprevention investigations?. J Natl Cancer Inst. 2003;95:E1
  36. Byers T. Nutrition and lung cancer: lessons from the differing effects of foods and supplements. Am J Respir Crit Care Med. 2008;177:470–471
  37. Micozzi MS, Brown ED, Edwards BK, Bieri JG, Taylor PR, Khachik F, et al. Plasma carotenoid response to chronic intake of selected foods and beta-carotene supplements in men. Am J Clin Nutr. 1992;55:1120–1125
  38. Brower V. An apple a day may be safer than vitamins. J Natl Cancer Inst. 2008;100:770–772
  39. Albanes D. Beta-carotene and lung cancer: a case study. Am J Clin Nutr. 1999;69:1345S–1350S
  40. van PG, Goldbohm RA. Epidemiologic evidence for beta-carotene and cancer prevention. Am J Clin Nutr. 1995;62:1393S–1402S
  41. Albanes D, Heinonen OP, Taylor PR, Virtamo J, Edwards BK, Rautalahti M, et al. Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst. 1996;88:1560–1570
  42. Greenwald P, Anderson D, Nelson SA, Taylor PR. Clinical trials of vitamin and mineral supplements for cancer prevention. Am J Clin Nutr. 2007;85:314S–317S
  43. World Cancer Research Fund. Food, nutrition, physical activity and the prevention of cancer—a global perspective. Washington, DC: AICR; 2007;
  44. Vastag B. Nutrients for prevention: negative trials send researchers back to drawing board. J Natl Cancer Inst. 2009;101:446–451
  45. Neuhouser ML, Wassertheil-Smoller S, Thomson C, Aragaki A, Anderson GL, Manson JE, et al. Multivitamin use and risk of cancer and cardiovascular disease in the Women's Health Initiative cohorts. Arch Intern Med. 2009;169:294–304
  46. World Cancer Research Fund. Dietary constituents and supplements. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. 1st ed.. Washington, DC: AICR; 2007;p. 179–89.

PII: S0169-5002(09)00587-X

doi: 10.1016/j.lungcan.2009.11.010

Lung Cancer
Volume 67, Issue 3 , Pages 275-281 , March 2010