Lung Cancer
Volume 70, Issue 2 , Pages 152-157 , November 2010

Copy number alterations and expression profiles of candidate genes in a pulmonary inflammatory myofibroblastic tumor

  • Seung-Hyun Jung

      Affiliations

    • Integrated Research Center for Genome Polymorphism, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • Department of Microbiology, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • ,
  • Seon-Hee Yim

      Affiliations

    • Integrated Research Center for Genome Polymorphism, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • Department of Hospital Pathology, Seoul St.Mary's Hospital, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • ,
  • Hae-Jin Hu

      Affiliations

    • Integrated Research Center for Genome Polymorphism, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • Department of Microbiology, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • ,
  • Chan-Kwon Jung

      Affiliations

    • Department of Hospital Pathology, Seoul St.Mary's Hospital, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • ,
  • Sug-Hyung Lee

      Affiliations

    • Department of Pathology, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • ,
  • Dong Hoon Kim

      Affiliations

    • Department of Pathology, Dankook University, College of Medicine, 29 Anseo-dong, Dongnam-gu, Cheonan-si, Chungnam 330-714, Republic of Korea
    • ,
  • Yeun-Jun Chung

      Affiliations

    • Integrated Research Center for Genome Polymorphism, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • Department of Microbiology, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea
    • Corresponding Author InformationCorresponding author at: Department of Microbiology, The Catholic University of Korea School of Medicine, 505 Banpo-dong, Seocho-gu, Seoul 137-701, Republic of Korea. Tel.: +82 2 2258 7343; fax: +82 2 537 0572.

Received 25 September 2009 ,Revised 8 January 2010 ,Accepted 29 January 2010.

References 

  1. In:  Travis WD,  Brambilla E,  Müller-Hermelink HK,  Harris CC editor. World Health Organization classification of tumours. Pathology and genetics of tumours of the lung, pleura, thymus and heart. Lyon: IARC Press; 2004;p. 105–106
  2. Coffin CM, Humphrey PA, Dehner LP. Extrapulmonary inflammatory myofibroblastic tumor: a clinical and pathological survey. Semin Diagn Pathol. 1998;15:85–101
  3. Su LD, Atayde-Perez A, Sheldon S, Fletcher JA, Weiss SW. Inflammatory myofibroblastic tumor: cytogenetic evidence supporting clonal origin. Mod Pathol. 1998;11:364–368
  4. Kovach SJ, Fischer AC, Katzman PJ, Salloum RM, Ettinghausen SE, Madeb R, et al. Inflammatory myofibroblastic tumors. J Surg Oncol. 2006;94:385–391
  5. Pinkel D, Segraves R, Sudar D, Clark S, Poole I, Kowbel D, et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet. 1998;20:207–211
  6. Kallioniemi A. CGH microarrays and cancer. Curr Opin Biotechnol. 2008;19:36–40
  7. Carvalho B, Ouwerkerk E, Meijer GA, Ylstra B. High resolution microarray comparative genomic hybridisation analysis using spotted oligonucleotides. J Clin Pathol. 2004;57:644–646
  8. Jung SH, Shin SH, Yim SH, Choi HS, Lee SH, Chung YJ. Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution whole-genome oligonucleotide array. Exp Mol Med. 2009;41:462–470
  9. Kim MY, Yim SH, Kwon MS, Kim TM, Shin SH, Kang HM, et al. Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization. Gastroenterology. 2006;131:1913–1924
  10. Jeong YB, Kim TM, Chung YJ. CGHscape: a software framework for the detection and visualization of copy number alterations. Genomics Inform. 2008;6:126–129
  11. Hupé P, Stransky N, Thiery JP, Radvanyi F, Barillot E. Analysis of array CGH data: from signal ratio to gain and loss of DNA regions. Bioinformatics. 2004;20:3413–3422
  12. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402–408
  13. Kim TM, Yim SH, Lee JS, Kwon MS, Ryu JW, Kang HM, et al. Genome-wide screening of genomic alterations and their clinicopathologic implications in non-small cell lung cancers. Clin Cancer Res. 2005;11:8235–8242
  14. Chujo M, Noguchi T, Miura T, Arinaga M, Uchida Y, Tagawa Y. Comparative genomic hybridization analysis detected frequent overrepresentation of chromosome 3q in squamous cell carcinoma of the lung. Lung Cancer. 2002;38:23–29
  15. Aviel-Ronen S, Coe BP, Lau SK, da Cunha Santos G, Zhu CQ, Strumpf D, et al. Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features. Proc Natl Acad Sci USA. 2008;105:10155–10160
  16. Garnis C, Lockwood WW, Vucic E, Ge Y, Girard L, Minna JD, et al. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer. 2006;118:1556–1564
  17. Shibata T, Uryu S, Kokubu A, Hosoda F, Ohki M, Sakiyama T, et al. Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features. Clin Cancer Res. 2005;11:6177–6185
  18. Massion PP, Kuo WL, Stokoe D, Olshen AB, Treseler PA, Chin K, et al. Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res. 2002;62:3636–3640
  19. Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, Roche J, et al. Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. Proc Natl Acad Sci USA. 2001;98:13954–13959
  20. Xiang R, Davalos AR, Hensel CH, Zhou XJ, Tse C, Naylor SL. Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice. Cancer Res. 2002;62:2637–2643
  21. Tse C, Xiang RH, Bracht T, Naylor SL. Human semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line. Cancer Res. 2002;62:542–546
  22. Brambilla E, Constantin B, Drabkin H, Roche J. Semaphorin SEMA3F localization in malignant human lung and cell lines: a suggested role in cell adhesion and cell migration. Am J Pathol. 2000;156:939–950
  23. Huang LR, Coughtrie MW, Hsu HC. Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma. Mol Cell Endocrinol. 2005;231:87–94
  24. Norppa H. Genetic susceptibility, biomarker responses, and cancer. Mutat Res. 2003;544:339–348
  25. Townsend DM, Tew KD. The role of glutathione-S-transferase in anticancer drug resistance. Oncogene. 2003;22:7369–7375
  26. Simic T, Mimic-Oka J, Savic-Radojevic A, Opacic M, Pljesa M, Dragicevic D, et al. Glutathione S-transferase T1-1 activity upregulated in transitional cell carcinoma of urinary bladder. Urology. 2005;65:1035–1040
  27. Holst F, Stahl PR, Ruiz C, Hellwinkel O, Jehan Z, Wendland M. Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Nat Genet. 2007;39:655–660

PII: S0169-5002(10)00062-0

doi: 10.1016/j.lungcan.2010.01.019

Lung Cancer
Volume 70, Issue 2 , Pages 152-157 , November 2010

Article Tools

* Image Usage & Resolution