Current Issue February 2012, Vol. 75, No. 2

The Italian Association of Thoracic Oncology (AIOT) was founded in July 2007 in order to improve knowledge and research in the field of thoracic oncology in Italy, through the collaboration of oncologists, radiotherapists, surgeons and researchers. The aim of the association is to create a platform for cultural and scientific discussion among the different professional trainers who play an important part in the diagnostic and therapeutic runs. A further aim is to support and increase clinical research and medical training.

The AIOT is also actively involved with the Italian School of Thoracic Oncology (SIOT) located in Frascati, Rome in the wonderful area of Castelli Romani, as well as in the organization of highly qualified educational events. Moreover with 380 members, the AIOT is currently setting up an international board of key opinion leaders.

• Correlations between serial pro-gastrin-releasing peptide and neuron-specific enolase levels, and the radiological response to treatment and survival of patients with small-cell lung cancer
  02 February 2012

  Akira Ono, Tateaki Naito, Ichiro Ito, Reiko Watanabe, Takehito Shukuya, Hirotsugu Kenmotsu, Asuka Tsuya, Yukiko Nakamura, Haruyasu Murakami, Kyoichi Kaira, Toshiaki Takahashi, Toru Kameya, Takashi Nakajima, Masahiro Endo, Nobuyuki Yamamoto

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  Abstract: Introduction: To investigate whether decrease in the serum levels of pro-gastrin releasing peptide (ProGRP) and neuron-specific enolase (NSE) were correlated with the radiological response i...

• Prognostic impact of education level of patients with advanced non-small cell lung cancer enrolled in clinical trials
  02 February 2012

  Massimo Di Maio, Simona Signoriello, Alessandro Morabito, Antonio Rossi, Paolo Maione, FrancoVito Piantedosi, Domenico Bilancia, Silvio Cigolari, Santi Barbera, Vittorio Gebbia, Bruno Daniele, Sergio Federico Robbiati, Alfonso Illiano, Anna Ceribelli, Francesco Carrozza, Adolfo Favaretto, Elena Piazza, Maria Carmela Piccirillo, Gennaro Daniele, Pasqualina Giordano, Raffaele Costanzo, Claudia Sandomenico, Gaetano Rocco, Ciro Gallo, Francesco Perrone, Cesare Gridelli

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  Abstract: Background: Socioeconomic status can potentially affect prognosis of cancer patients. Our aim was to describe potential differences in demographic and clinical characteristics, treatment, an...

• Stromal CD4/CD25 positive T-cells are a strong and independent prognostic factor in non-small cell lung cancer patients, especially with adenocarcinomas
  02 February 2012

  Gian Kayser, Luzie Schulte-Uentrop, Wulf Sienel, Martin Werner, Paul Fisch, Bernward Passlick, Axel zur Hausen, Christian Stremmel

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  Abstract: Within the concert of immune reactions against tumour cells cytotoxic and regulatory T-cells are of utmost importance. Several studies revealed contradictory results on this issue. We theref...

• Stereotactic body radiotherapy (SBRT) for solitary pulmonary nodules clinically diagnosed as lung cancer with no pathological confirmation: Comparison with non-small-cell lung cancer
  02 February 2012

  Atsuya Takeda, Etsuo Kunieda, Naoko Sanuki, Yousuke Aoki, Yohei Oku, Hiroshi Handa

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  Abstract: Introduction: In non-surgical candidates with solitary pulmonary nodules (SPNs) and no histological confirmation, optimal management remains uncertain. Methods: Between February 2005 and Feb...

• When will I get my breath back? Recovery time of exercise-induced breathlessness in patients with thoracic cancer
  30 January 2012

  Matthew Maddocks, Victoria Taylor, Radka Klezlova, Ruth England, Cathann Manderson, Andrew Wilcock

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  Breathlessness is a common symptom in thoracic cancer. It impacts adversely on physical activity levels and the resultant deconditioning may exacerbate the decline in physical capacity . Therapeutic e...

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