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Editorial Board
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iii
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Contents
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v-vi
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| Reviews |
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PET scans in radiotherapy planning of lung cancer
19 September 2011
Abstract: Accurate delineation of the primary tumor and of involved lymph nodes is a key requisite for successful curative radiotherapy in non-small cell lung cancer (NSCLC). In recent years, it has b...
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Dirk De Ruysscher,
Ursula Nestle,
Robert Jeraj,
Michael MacManus
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141-145
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Implementation of hypoxia measurement into lung cancer therapy
17 October 2011
Abstract: Tumor hypoxia has been found to be a characteristic feature in lung cancer. It has been shown to decrease the therapeutic efficacy of radiotherapy and some forms of chemotherapy. New methods...
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Xue Meng,
Feng-Ming (Spring) Kong,
Jinming Yu
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146-150
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| Epidemiology |
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Cancer mortality among Chinese chrysotile asbestos textile workers
28 July 2011
Abstract: To determine mortality associated with exposure to chrysotile asbestos, a cohort of asbestos workers from an asbestos textile factory in China was followed prospectively from 1972 to 2008. A...
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X.R. Wang,
I.T.S. Yu,
H. Qiu,
M.Z. Wang,
Y.J. Lan,
L.Y. Tse,
E. Yano,
D.C. Christiani
et al.
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151-155
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Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development
12 August 2011
Abstract: Background: In a European multicenter prospective study patients with lung cancer were interviewed for smoking history and biological samples centrally collected. The aim of this study was t...
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F.B. Thunnissen,
C. Prinsen,
B. Hol,
M. Van der Drift,
A. Vesin,
C. Brambilla,
L. Montuenga,
J.K. Field,
the EUELC consortium
et al.
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156-160
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| Carcinogenesis and molecular biology |
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Author(s) |
Pages |
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The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor
18 July 2011
Abstract: Acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), gefitinib and erlotinib, is frequently observed after initiation of TKIs therapy. Non-small-ce...
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Naruyuki Kobayashi,
Shinichi Toyooka,
Junichi Soh,
Hiromasa Yamamoto,
Hideaki Dote,
Kensuke Kawasaki,
Hiroki Otani,
Takafumi Kubo,
Masaru Jida,
Tsuyoshi Ueno,
Midori Ando,
Atsuko Ogino,
Katsuyuki Kiura,
Shinichiro Miyoshi
et al.
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161-166
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Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway
29 July 2011
Abstract: Background: The role of mesenchymal stem cells (MSCs) and IL-6 in lung cancer has not been well-addressed. We aimed to determine if MSCs can enhance the ability of tumor initiation of lung c...
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Han-Shui Hsu,
Jiun-Han Lin,
Tien-Wei Hsu,
Kelly Su,
Cheng-Wien Wang,
Kuang-Yao Yang,
Shih-Hwa Chiou,
Shih-Chieh Hung
et al.
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167-177
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| Diagnosis and pathology |
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Article Title |
Author(s) |
Pages |
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Exhaled breath condensate pH in patients with lung cancer
10 August 2011
Abstract: Assessment of exhaled breath condensate (EBC) pH is a promising method for investigating and monitoring airway pathology in a number of lung diseases. In this cross-sectional study we tested...
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Balazs Antus,
Imre Barta
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178-180
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Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis
29 August 2011
Abstract: Background: Signaling mediated by hepatocyte growth factor (HGF)/MET promotes multiple biological activities, including cell proliferation, motility, invasion, angiogenesis, and morphogenesi...
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Keisei Tachibana,
Yuko Minami,
Aya Shiba-Ishii,
Junko Kano,
Yoshimasa Nakazato,
Yukio Sato,
Tomoyuki Goya,
Masayuki Noguchi
et al.
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181-188
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Proteomic surfaceome analysis of mesothelioma
11 August 2011
Abstract: Identification of new markers for malignant pleural mesothelioma (MPM) is a challenging clinical need. Here, we propose a quantitative proteomics primary screen of the cell surface exposed M...
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Annemarie Ziegler,
Ferdinando Cerciello,
Colette Bigosch,
Damaris Bausch-Fluck,
Emanuela Felley-Bosco,
Reto Ossola,
Alex Soltermann,
Rolf A. Stahel,
Bernd Wollscheid
et al.
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189-196
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| Imaging |
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Long-term prognosis of patients with lung cancer detected on low-dose chest computed tomography screening
03 August 2011
Abstract: The effectiveness of lung cancer screening using low-dose chest computed tomography (CT) remains elusive. The present study examined the prognosis of patients with lung cancer detected on CT...
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Takeshi Nawa,
Tohru Nakagawa,
Tetsuya Mizoue,
Suzushi Kusano,
Tatsuya Chonan,
Shimao Fukai,
Katsuyuki Endo
et al.
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197-202
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| Treatment |
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Author(s) |
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Safety and feasibility of a combined exercise intervention for inoperable lung cancer patients undergoing chemotherapy: A pilot study
04 August 2011
Abstract: Aim: To investigate the safety and feasibility of a six-week supervised structured exercise and relaxation training programme on estimated peak oxygen consumption, muscle strength and health...
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Morten Quist,
Mikael Rørth,
Seppo Langer,
Lee W. Jones,
Jørgen H. Laursen,
Helle Pappot,
Karl Bang Christensen,
Lis Adamsen
et al.
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203-208
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Prediction of the prognosis and surgical indications for pulmonary metastectomy from colorectal carcinoma in patients with combined hepatic metastases
08 August 2011
Abstract: Background: The value of surgical treatment for patients with pulmonary and hepatic metastases from colorectal carcinoma is controversial. The purpose of this study was to analyze our initia...
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Daigo Kawano,
Sadanori Takeo,
Shuichi Tsukamoto,
Masakazu Katsura,
Eri Masuyama,
Yu Nakaji
et al.
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209-212
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Epirubicin and ifosfamide in relapsed or refractory small cell lung cancer patients
10 August 2011
Abstract: Introduction: In small cell lung cancer (SCLC), despite the high response rates induced by platinum-based first line chemotherapies, relapse happens in 85% of the first-line responding tumor...
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William Jacot,
Jean-Louis Pujol,
Mohammad Chakra,
Olivier Molinier,
Marie-Cécile Bozonnat,
Radj Gervais,
Xavier Quantin
et al.
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213-216
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| Clinical correlates |
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Author(s) |
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Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: A verification study
01 August 2011
Abstract: Background: A recent study by Dhillon et al. , identified both angioinvasion and mTOR as prognostic biomarkers for poor survival in early stage NSCLC. The aim of this study was to verify the...
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K. Gately,
B. Al-Alao,
T.Dhillon,
F. Mauri,
S. Cuffe,
M. Seckl,
K. O’Byrne
et al.
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217-222
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Preoperative lymphocyte count is an independent prognostic factor in node-negative non-small cell lung cancer
18 July 2011
Abstract: A number of prognostic factors have been reported in non-small cell lung cancer (NSCLC). Although lymph node metastasis is the most poorly predictive value in completely resected NSCLC, a si...
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Naohiro Kobayashi,
Shingo Usui,
Shinji Kikuchi,
Yukinobu Goto,
Mitsuaki Sakai,
Masataka Onizuka,
Yukio Sato
et al.
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223-227
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Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy
26 July 2011
Abstract: Background: Recent studies have shown that human copper transporter 1 (hCtr1), the major copper influx transporter, is involved in the transport of platinum-based antitumor agents. We invest...
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Helen H.W. Chen,
Jiang-Jou Yan,
Wen-Chung Chen,
Macus Tien Kuo,
Yu-Hsuan Lai,
Wu-Wei Lai,
Hsiao-Sheng Liu,
Wu-Chou Su
et al.
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228-234
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Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome
18 July 2011
Abstract: Background: Matrix metalloproteinases (MMPs) are considered important players in angiogenesis and cancer progression. Several drugs developed for targeting MMPs have until now been without c...
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Helge Stenvold,
Tom Donnem,
Sigve Andersen,
Samer Al-Saad,
Khalid Al-Shibli,
Lill-Tove Busund,
Roy M. Bremnes
et al.
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235-241
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Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis
05 August 2011
Abstract: Background: The aim of this study was to explore circulating tumor cell (CTC) detection in advanced non-small cell lung cancer (NSCLC). CTCs may not only serve as a prognostic marker in sele...
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L.A. Devriese,
A.J. Bosma,
M.M. van de Heuvel,
W. Heemsbergen,
E.E. Voest,
J.H.M. Schellens
et al.
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242-247
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The predictive role of serum VEGF in an advanced malignant mesothelioma patient cohort treated with thalidomide alone or combined with cisplatin/gemcitabine
15 July 2011
Abstract: There is a need for new treatment strategies and prognostic markers for the management of malignant mesothelioma (MM). The activity of thalidomide/cisplatin/gemcitabine (arm A) or thalidomid...
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Steven Chuan-Hao Kao,
Rozelle Harvie,
Florian Paturi,
Robyn Taylor,
Ross Davey,
Rick Abraham,
Stephen Clarke,
Gavin Marx,
Martin Cullen,
Zoltan Kerestes,
Nick Pavlakis
et al.
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248-254
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| Outcomes |
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Article Title |
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Pages |
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Factors associated with adherence to chemotherapy guidelines in patients with non-small cell lung cancer
04 August 2011
Summary: Background: Evidence-based guidelines recommend chemotherapy for medically fit patients with stages II–IV non-small cell lung cancer (NSCLC). Adherence to chemotherapy guidelines has rarely b...
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Ramzi G. Salloum,
Thomas J. Smith,
Gail A. Jensen,
Jennifer Elston Lafata
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255-260
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Raltitrexed plus cisplatin is cost-effective compared with pemetrexed plus cisplatin in patients with malignant pleural mesothelioma
21 September 2011
Abstract: Introduction: The National Institute for Health and Clinical Excellence (NICE) has previously recommended pemetrexed plus cisplatin for the treatment of patients with advanced malignant pleu...
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Beth Woods,
Noman Paracha,
David A. Scott,
Nicholas Thatcher
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261-267
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